Creative Biogene Enhances Production of Premium E. coli strain
Creative Biogene, an international biotechnology company, announced that it has optimized a microbial production platform for E. coli strain of high purity, excellent stability, and sustainable supply. The final product form can be customized according to the formulation needs of cosmetics.
Ergothioneine is a sulfur-containing histidine derivative that was discovered in 1909. Ergothioneine is only naturally produced by some fungi and bacteria, such as Neurospora crassa and Mycobacterium smegmatis. Ergothioneine is a highly potent and stable natural antioxidant, with the ability to scavenge ROS and chelate divalent metal ions (Fe2+, Cu2+) in biological systems, thereby protecting cells against oxidative stress.
Creative Biogene used microbial fermentation technology and metabolic pathway engineering to produce cosmetic-grade Ergothioneine with purity ≥98%, which can be used directly in skincare products to meet quality standards, and provides cosmetics brands with a scalable production platform for premium, efficacy-backed, and sustainable ingredients for skin care products.
“Ergothioneine is a multifunctional ingredient, well-known for its antioxidant capabilities,” the chief scientist of Creative Biogene added. ”It is also an effective multifunctional cosmetic ingredient.”
Uses of Cosmetic-Grade Ergothioneine:
- Antioxidant: Used in anti-oxidative stress formulations caused by the environment.
- Anti-inflammatory: Used in calming and soothing products.
- Anti-aging: Used in skincare products to help overall skin condition and appearance.
- Metal-chelating: Used as a metal ion chelator in products.
In addition to cosmetics applications, Ergothioneine can also be applied in food and biotechnology.
Creative Biogene also provides efficacy evaluation services for Ergothioneine, including in vitro efficacy evaluation using a human skin tissue model to assess hydration, skin barrier, anti-inflammatory and antioxidation properties as well as ex vivo penetration testing using human skin samples. This allows cosmetic brands to ensure a strong development pipeline and meet regulatory requirements.
About Creative Biogene
Creative Biogene provides integrated biotechnology services including strain development, fermentation optimization, downstream purification, analytical testing, and GMP-compliant manufacturing. With its optimized Ergothioneine production technology, Creative Biogene aims to help the cosmetics industry deliver innovative, effective, and sustainable products to improve consumers’ lives.